Possible Implication of Nrf2, PPAR-γ and MAPKs Signaling in the Protective Role of Mangiferin against Renal Ischemia/Reperfusion in Rats

• Main Authors: Abdallah M. Gendy (Author), Amira A. El-Gazar (Author), Ghada M. Ragab (Author), Asmaa K. Al-Mokaddem (Author), Alaadin E. El-Haddad (Author), Heba Mohammed Refat M. Selim (Author), Einas Mohamed Yousef (Author), Najat O. Hamed (Author), Sherihan Salaheldin Abdelhamid Ibrahim (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mangiferin (Mang) is a known glucosylxanthone that has proven its shielding effect against ischemia/reperfusion (Is/R). However, its full underlying mechanistic perspective against renal Is/R induced lesions is not fully revealed. Consequently, the purpose of this study is to track further non-inves...