Population Pharmacokinetic Model of Plasma and Cellular Mycophenolic Acid in Kidney Transplant Patients from the CIMTRE Study

• Main Authors: François Riglet (Author), Julie Bertrand (Author), Aurélie Barrail-Tran (Author), Céline Verstuyft (Author), Hugues Michelon (Author), Henri Benech (Author), Antoine Durrbach (Author), Valérie Furlan (Author), Caroline Barau (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background and Objective Mycophenolate mofetil is widely used in kidney transplant recipients. Mycophenolate mofetil is hydrolysed by blood esterases to mycophenolic acid (MPA), the active drug. Although MPA therapeutic drug monitoring has been recommended to optimise the treatment efficacy...