Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report

• Main Authors: Robina Khan Niazi (Author), Anette Prior Gjesing (Author), Mette Hollensted (Author), Christian Theil Have (Author), Dmitrii Borisevich (Author), Niels Grarup (Author), Oluf Pedersen (Author), Asmat Ullah (Author), Gulbin Shahid (Author), Ifrah Shafqat (Author), Asma Gul (Author), Torben Hansen (Author)
• Format: Book
• Published: BMC, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Consanguine families display a high degree of homozygosity which increases the risk of family members suffering from autosomal recessive disorders. Thus, homozygous mutations in monogenic obesity genes may be a more frequent cause of childhood obesity in a consanguineous populati...