AMPK Activator O304 Protects Against Kidney Aging Through Promoting Energy Metabolism and Autophagy

• Main Authors: Mingsheng Zhu (Author), Weiwei Shen (Author), Jiemei Li (Author), Nan Jia (Author), Yabing Xiong (Author), Jinhua Miao (Author), Chao Xie (Author), Qiyan Chen (Author), Kunyu Shen (Author), Ping Meng (Author), Xiaolong Li (Author), Qinyu Wu (Author), Shan Zhou (Author), Maosheng Wang (Author), Yaozhong Kong (Author), Lili Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aging is an important risk factor for kidney injury. Energy homeostasis plays a key role in retarding aging, and mitochondria are responsible for energy production. In the kidney, renal tubular cells possess high abundance of mitochondria to meet the high energy consumption. AMPK is an evolutionaril...