Hyperferritinaemia in dengue virus infected patients is associated with immune activation and coagulation disturbances.

• المؤلفون الرئيسيون: Cornelia A M van de Weg (مؤلف), Ralph M H G Huits (مؤلف), Cláudio S Pannuti (مؤلف), Rosalba M Brouns (مؤلف), Riemsdijk W A van den Berg (مؤلف), Henk-Jan van den Ham (مؤلف), Byron E E Martina (مؤلف), Albert D M E Osterhaus (مؤلف), Mihai G Netea (مؤلف), Joost C M Meijers (مؤلف), Eric C M van Gorp (مؤلف), Esper G Kallas (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

During a dengue outbreak on the Caribbean island Aruba, highly elevated levels of ferritin were detected in dengue virus infected patients. Ferritin is an acute-phase reactant and hyperferritinaemia is a hallmark of diseases caused by extensive immune activation, such as haemophagocytic lymphohistio...