IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway

• Автори: Ming-Siou Chen (Автор), Cheng-Yu Lin (Автор), Yun-Hsuan Chiu (Автор), Chie-Pein Chen (Автор), Pei-Jiun Tsai (Автор), Hwai-Shi Wang (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2018-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear. In this study, we found that the proinflammation cytokine interleukin-1β (IL-1β) promotes m...