Allicin Induces Calcium and Mitochondrial Dysregulation Causing Necrotic Death in Leishmania.

• मुख्य लेखकों: María J Corral (लेखक), Elena Benito-Peña (लेखक), M Dolores Jiménez-Antón (लेखक), Laureano Cuevas (लेखक), María C Moreno-Bondi (लेखक), José M Alunda (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND:Allicin has shown antileishmanial activity in vitro and in vivo. However the mechanism of action underlying its antiproliferative effect against Leishmania has been virtually unexplored. In this paper, we present the results obtained in L.infantum and a mechanistic basis is proposed. METH...