P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation

Protein allosteric modulation is a pillar of metabolic regulatory mechanisms; this concept has been extended to include ion channel regulation. P2XRs are ligand-gated channels activated by extracellular ATP, sensitive to trace metals and other chemicals. By combining in silico calculations with elec...

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Bibliographic Details
Main Authors: Verónica Latapiat (Author), Felipe E. Rodríguez (Author), Francisca Godoy (Author), Felipe A. Montenegro (Author), Nelson P. Barrera (Author), Juan P. Huidobro-Toro (Author)
Format: Book
Published: Frontiers Media S.A., 2017-12-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available