Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily

• Principais autores: Guillem Prats-Ejarque (Autor), Lu Lu (Autor), Vivian A. Salazar (Autor), Mohammed Moussaoui (Autor), Ester Boix (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

There is a growing interest in the pharmaceutical industry to design novel tailored drugs for RNA targeting. The vertebrate-specific RNase A superfamily is nowadays one of the best characterized family of enzymes and comprises proteins involved in host defense with specific cytotoxic and immune-modu...