Cathepsin B-activatable cyclic antisense oligonucleotides for cell-specific target gene knockdown in vitro and in vivo

Trigger-activatable antisense oligonucleotides have been widely applied to regulate gene function. Among them, caged cyclic antisense oligonucleotides (cASOs) maintain a specific topology that temporarily inhibits their interaction with target genes. By inserting linkers that respond to cell-specifi...

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Bibliographic Details
Main Authors: Zhongyu Wang (Author), Xinli Fan (Author), Guanqun Mu (Author), Xiaoran Zhao (Author), Qian Wang (Author), Jing Wang (Author), Xinjing Tang (Author)
Format: Book
Published: Elsevier, 2023-09-01T00:00:00Z.
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