Computational Drug Repurposing for Alzheimer's Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies

• المؤلفون الرئيسيون: Yun Xu (مؤلف), Jiming Kong (مؤلف), Pingzhao Hu (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background: Traditional therapeutics targeting Alzheimer's disease (AD)-related subpathologies have so far proved ineffective. Drug repurposing, a more effective strategy that aims to find new indications for existing drugs against other diseases, offers benefits in AD drug development. In this...