Metabolomic landscape of macrophage discloses an anabolic signature of dengue virus infection and antibody-dependent enhancement of viral infection.

• Main Authors: Li Xu (Author), Min Li (Author), Jingpu Zhang (Author), Dongxiao Li (Author), Jie Tao (Author), Fuchun Zhang (Author), Xia Jin (Author), Jiahai Lu (Author), Tiefu Liu (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue virus (DENV) infection causes dengue fever, the most prevalent arthropod-transmitted viral disease worldwide. Viruses are acellular parasites and obligately rely on host cell machinery for reproduction. Previous studies have indicated metabolomic changes in endothelial cell models and sera of...