Intermedin Alleviates Diabetic Cardiomyopathy by Up-Regulating CPT-1β through Activation of the Phosphatidyl Inositol 3 Kinase/Protein Kinase B Signaling Pathway

• Main Authors: Jie Zhao (Author), Ling Han (Author), Ya-Rong Zhang (Author), Shi-Meng Liu (Author), Deng-Ren Ji (Author), Rui Wang (Author), Yan-Rong Yu (Author), Mo-Zhi Jia (Author), San-Bao Chai (Author), Hui-Fang Tang (Author), Wei Huang (Author), Yong-Fen Qi (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic cardiomyopathy (DCM), one of the most serious long-term consequences of diabetes, is closely associated with myocardial fatty acid metabolism. Carnitine palmitoyltransferase-1β (CPT-1β) is the rate-limiting enzyme responsible for β-oxidation of long-chain fatty acids. Intermedin (IMD) is a...