Melatonin Protects against the Side-Effects of 5-Fluorouracil on Hippocampal Neurogenesis and Ameliorates Antioxidant Activity in an Adult Rat Hippocampus and Prefrontal Cortex

• मुख्य लेखकों: Kornrawee Suwannakot (लेखक), Nataya Sritawan (लेखक), Ram Prajit (लेखक), Anusara Aranarochana (लेखक), Apiwat Sirichoat (लेखक), Wanassanun Pannangrong (लेखक), Peter Wigmore (लेखक), Jariya Umka Welbat (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Melatonin is an endogenous hormone that exhibits antioxidant functions and neuroprotective effects. The hippocampus and the prefrontal cortex (PFC) play an important role linked to working memory. 5-fluorouracil (5-FU) can induce oxidative stress and reduce neurogenesis in the subgranular zone (SGZ)...