Efficacy of inverso isomer of CendR peptide on tumor tissue penetration

• Main Authors: Ruifeng Wang (Author), Qing Shen (Author), Xue Li (Author), Cao Xie (Author), Weiyue Lu (Author), Songli Wang (Author), Jing Wang (Author), Dongli Wang (Author), Min Liu (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The dense extracellular matrix and high interstitial fluid pressure of tumor tissues prevent the ability of anti-tumor agents to penetrate deep into the tumor parenchyma for treatment effects. C-end rule (CendR) peptides can enhance the permeability of tumor blood vessels and tumor tissues via bindi...