Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance

• Main Authors: Rui-Qiang Zhao (Author), Yan Wen (Author), Pranav Gupta (Author), Zi-Ning Lei (Author), Chao-Yun Cai (Author), Gang Liang (Author), Dong-Hua Yang (Author), Zhe-Sheng Chen (Author), Yu-An Xie (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters. ABC subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which have been implicated as a key co...