Molecular and Kinetic Characterization of Gray Strain Lactate Dehydrogenase as a Potential Drug Target

• Main Authors: Patrick Vudriko (Author), Tatsunori Masatani (Author), Shinuo Cao (Author), Mohamad Alia Terkawi (Author), Ketsarin Kamyingkird (Author), Ahmed A. Mousa (Author), Paul F. Adjou Moumouni (Author), Yoshifumi Nishikawa (Author), Xuenan Xuan (Author)
• Format: Book
• Published: AboutScience Srl, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Babesia microti is an emerging zoonotic protozoan organism that causes "malaria-like" symptoms that can be fatal in immunocompromised people. Owing to lack of specific therapeutic regiment against the disease, we cloned and characterized B. microti lactate dehydrogenase (BmLDH) as a potent...