Application of an assay Cascade methodology for a deep preclinical characterization of polymeric nanoparticles as a treatment for gliomas

• Main Authors: Cristina Fornaguera (Author), Miguel Ángel Lázaro (Author), Pau Brugada-Vilà (Author), Irene Porcar (Author), Ingrid Morera (Author), Marta Guerra-Rebollo (Author), Cristina Garrido (Author), Núria Rubio (Author), Jerónimo Blanco (Author), Anna Cascante (Author), Salvador Borrós (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is the most devastating primary brain tumor due to its infiltrating and diffuse growth characteristics, a situation compounded by the lack of effective treatments. Currently, many efforts are being devoted to find novel formulations to treat this disease, specifically i...