LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2

• Main Authors: Cheng Zhang (Author), Tong Kang (Author), Xinyi Wang (Author), Jizhao Wang (Author), Lin Liu (Author), Jiawei Zhang (Author), Xu Liu (Author), Rong Li (Author), Jiansheng Wang (Author), Jia Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Resistance to cisplatin (DDP) is a major obstacle in the clinical treatment of advanced gastric cancer (GC). Long noncoding RNA (lncRNA) play a significant regulatory role in the development and drug resistance of GC. In this study, we reported that the lncRNA LINC-PINT was downregulated in DDP-resi...