LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2

• मुख्य लेखकों: Cheng Zhang (लेखक), Tong Kang (लेखक), Xinyi Wang (लेखक), Jizhao Wang (लेखक), Lin Liu (लेखक), Jiawei Zhang (लेखक), Xu Liu (लेखक), Rong Li (लेखक), Jiansheng Wang (लेखक), Jia Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Resistance to cisplatin (DDP) is a major obstacle in the clinical treatment of advanced gastric cancer (GC). Long noncoding RNA (lncRNA) play a significant regulatory role in the development and drug resistance of GC. In this study, we reported that the lncRNA LINC-PINT was downregulated in DDP-resi...