Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor

• Үндсэн зохиолчид: Qing-Yan Yang (Зохиогч), Ya-Hui Hu (Зохиогч), Hong-Li Guo (Зохиогч), Ying Xia (Зохиогч), Yong Zhang (Зохиогч), Wei-Rong Fang (Зохиогч), Yun-Man Li (Зохиогч), Jing Xu (Зохиогч), Feng Chen (Зохиогч), Yong-Ren Wang (Зохиогч), Teng-Fei Wang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Vincristine (VCR) is the first-line chemotherapeutic medication often co-administered with other drugs to treat childhood acute lymphoblastic leukemia. Dose-dependent neurotoxicity is the main factor restricting VCR's clinical application. VCR-induced peripheral neuropathy (VIPN) sometimes resu...