Beta2-Adrenergic Receptor Polymorphisms and Haplotypes Associate With Chronic Pain in Sickle Cell Disease

Beta2-Adrenergic Receptor Polymorphisms and Haplotypes Associate With Chronic Pain in Sickle Cell Disease

Pain in sickle cell disease (SCD) is severe, variable, and inadequately comprehended. The β2-adrenergic receptor (ADRB2) is critical in mediating neurotransmitter response in the sympathetic nervous system. In this association study, we examined 16 single nucleotide polymorphisms (SNPs) covering 5&#...

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Main Authors: Ellie H. Jhun (Author), Nilanjana Sadhu (Author), Xiaoyu Hu (Author), Yingwei Yao (Author), Ying He (Author), Diana J. Wilkie (Author), Robert E. Molokie (Author), Zaijie Jim Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
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