Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells

• Main Authors: Domitilla Schiumarini (Author), Nicoletta Loberto (Author), Giulia Mancini (Author), Rosaria Bassi (Author), Paola Giussani (Author), Elena Chiricozzi (Author), Maura Samarani (Author), Silvia Munari (Author), Anna Tamanini (Author), Giulio Cabrini (Author), Giuseppe Lippi (Author), Maria Cristina Dechecchi (Author), Sandro Sonnino (Author), Massimo Aureli (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis (CF) is the most common autosomal genetic recessive disease caused by mutations of gene encoding for the cystic fibrosis transmembrane conductance regulator. Patients with CF display a wide spectrum of symptoms, the most severe being chronic lung infection and inflammation, which lea...