PK/PD modeling analysis for dosing regimen selection of isatuximab as single agent and in combination therapy in patients with multiple myeloma

PK/PD modeling analysis for dosing regimen selection of isatuximab as single agent and in combination therapy in patients with multiple myeloma

Abstract This analysis describes the pharmacokinetic/pharmacodynamic (PK/PD) modeling framework that supported selection of the isatuximab (anti‐CD38 monoclonal antibody) dosing regimen alongside its early clinical development in patients with relapsed/refractory multiple myeloma (RRMM). The PK/PD m...

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Main Authors: Kimiko Koiwai (Author), Raouf El‐Cheikh (Author), Hoai‐Thu Thai (Author), Claire Brillac (Author), Jean‐Baptiste Fau (Author), Christine Veyrat‐Follet (Author), Marie‐Laure Risse (Author), Helgi van deVelde (Author), Dorothée Semiond (Author), Laurent Nguyen (Author)
Format: Book
Published: Wiley, 2021-08-01T00:00:00Z.
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