IFN-γ plays a unique role in protection against low virulent Trypanosoma cruzi strain.

• Main Authors: Adele A Rodrigues (Author), Jasson S S Saosa (Author), Grace K da Silva (Author), Flávia A Martins (Author), Aline A da Silva (Author), Cecílio P da Silva Souza Neto (Author), Catarina V Horta (Author), Dario S Zamboni (Author), João S da Silva (Author), Eloisa A V Ferro (Author), Claudio V da Silva (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: T. cruzi strains have been divided into six discrete typing units (DTUs) according to their genetic background. These groups are designated T. cruzi I to VI. In this context, amastigotes from G strain (T. cruzi I) are highly infective in vitro and show no parasitemia in vivo. Here we aim...