Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity

• Main Authors: Long Cui (Author), Fang Zhou (Author), Cui Chen (Author), Chi Chiu Wang (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objectives The aim of the study is to explore the relationship between CCDC69 expression and resistance of ovarian cancer cells to cisplatin and reveal the underlying mechanism. Methods One hundred thirty five ovarian cancer patients with intact chemo-response information from The Cancer Ge...