Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro

• Main Authors: Christelle Rosazza (Author), Hendrik Deschout (Author), Annette Buntz (Author), Kevin Braeckmans (Author), Marie-Pierre Rols (Author), Andreas Zumbusch (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA electrotransfer is a successful technique for gene delivery into cells and represents an attractive alternative to virus-based methods for clinical applications including gene therapy and DNA vaccination. However, little is currently known about the mechanisms governing DNA internalization and i...