Low frequency of circulating CD8+ T stem cell memory cells in chronic chagasic patients with severe forms of the disease.

• Main Authors: Jose Mateus (Author), Paola Lasso (Author), Paula Pavia (Author), Fernando Rosas (Author), Nubia Roa (Author), Carlos Andrés Valencia-Hernández (Author), John Mario González (Author), Concepción J Puerta (Author), Adriana Cuéllar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD8+ T cells have been shown to play a crucial role in Trypanosoma cruzi infection. Memory CD8+ T cells can be categorised based on their distinct differentiation stages and functional activities as follows: stem cell memory (TSCM), central memory (TCM), transitional memory (TTM), effector memory (T...