Suppression of CRLF1 promotes the chondrogenic differentiation of bone marrow-derived mesenchymal stem and protects cartilage tissue from damage in osteoarthritis via activation of miR-320

• Autores principales: Hao Xu (Autor), Changrong Ding (Autor), Cuicui Guo (Autor), Shuai Xiang (Autor), Yingzhen Wang (Autor), Bing Luo (Autor), Hongfei Xiang (Autor)
• Formato: Libro
• Publicado: BMC, 2021-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Osteoarthritis (OA) is the most prevalent chronic joint disease, and is hard to be cured at present. Cytokine receptor-like factor 1 (CRLF1) has been identified as an upregulated gene in OA cartilage. However, the precise identities and functions of CRLF1 in OA progression have r...