Study of potential xanthine oxidase inhibitors: In silico and in vitro biological activity

• Auteurs principaux: Muthuswamy Umamaheswari (Auteur), Arumugam Madeswaran (Auteur), Kuppusamy Asokkumar (Auteur), Thirumalaisamy Sivashanmugam (Auteur), Varadharajan Subhadradevi (Auteur), Puliyath Jagannath (Auteur)
• Format: Livre
• Publié: Bangladesh Pharmacological Society, 2011-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

In an attempt to develop potent anti gout agents, coumarin derivatives and polyphenolic compounds were selected for present study. The docking energy of 2-benzyl coumarin was found to be -7.50 kcal/mol which was less than that of the standard allopurinol (-4.47 kcal/mol). All the selected compounds...