Study of potential xanthine oxidase inhibitors: In silico and in vitro biological activity

• Main Authors: Muthuswamy Umamaheswari (Author), Arumugam Madeswaran (Author), Kuppusamy Asokkumar (Author), Thirumalaisamy Sivashanmugam (Author), Varadharajan Subhadradevi (Author), Puliyath Jagannath (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In an attempt to develop potent anti gout agents, coumarin derivatives and polyphenolic compounds were selected for present study. The docking energy of 2-benzyl coumarin was found to be -7.50 kcal/mol which was less than that of the standard allopurinol (-4.47 kcal/mol). All the selected compounds...