Harnessing endoscopic ultrasound-guided radiofrequency ablation to reshape the pancreatic ductal adenocarcinoma microenvironment and elicit systemic immunomodulation

• Main Authors: Vishali Moond (Author), Bhumi Maniyar (Author), Prateek Suresh Harne (Author), Jennifer M. Bailey-Lundberg (Author), Nirav C. Thosani (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognostics and substantial therapeutic challenges, with dismal survival rates. Tumor resistance in PDAC is primarily attributed to its fibrotic, hypoxic, and immune-suppressive tumor microenvironment (TME). Endoscopic ultrasound-guide...