NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation

NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation

(1) Background: Early response after acute myocardial infarction (AMI) prevents extensive cardiac necrosis, in which inflammation resolution, including expression of anti-inflammatory interleukin-10 (IL-10), may play a key role. (2) Methods: We synthesized NIL10, a micelle-based nanoparticle, to tar...

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Main Authors: Laura Tesoro (Author), Ignacio Hernández (Author), Rafael Ramírez-Carracedo (Author), Javier Díez-Mata (Author), Nunzio Alcharani (Author), Beatriz Jiménez-Guirado (Author), Karina Ovejero-Paredes (Author), Marco Filice (Author), Jose Luis Zamorano (Author), Marta Saura (Author), Carlos Zaragoza (Author), Laura Botana (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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