Pre-Clinical Investigation of Liquid Paclitaxel for Local Drug Delivery: A Pilot Study

• Main Authors: Claire V. Cawthon (Author), Kathryn Cooper (Author), Clifton Huett (Author), Alyssa Lloret (Author), Estefanny Villar-Matamoros (Author), Lauren Stokes (Author), Uwe Christians (Author), Michele Schuler (Author), Saami K. Yazdani (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this pilot study was to investigate the feasibility of a perfusion catheter to deliver liquid paclitaxel into arterial segments. A clinically relevant rabbit ilio-femoral injury model was utilized to determine the impact of liquid paclitaxel delivered locally into the vessel wall usin...