Pre-Clinical Investigation of Liquid Paclitaxel for Local Drug Delivery: A Pilot Study

• Autori principali: Claire V. Cawthon (Autore), Kathryn Cooper (Autore), Clifton Huett (Autore), Alyssa Lloret (Autore), Estefanny Villar-Matamoros (Autore), Lauren Stokes (Autore), Uwe Christians (Autore), Michele Schuler (Autore), Saami K. Yazdani (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2020-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The purpose of this pilot study was to investigate the feasibility of a perfusion catheter to deliver liquid paclitaxel into arterial segments. A clinically relevant rabbit ilio-femoral injury model was utilized to determine the impact of liquid paclitaxel delivered locally into the vessel wall usin...