Recombinant Newcastle disease virus (NDV/Anh-IL-2) expressing human IL-2 as a potential candidate for suppresses growth of hepatoma therapy

• Main Authors: Yunzhou Wu (Author), Jinjiao He (Author), Ying An (Author), Xi Wang (Author), Yunye Liu (Author), Shijun Yan (Author), Xianlong Ye (Author), Jianying Qi (Author), Shenglong Zhu (Author), Qingzhong Yu (Author), Jiechao Yin (Author), Deshan Li (Author), Wenfei Wang (Author)
• Format: Book
• Published: Elsevier, 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Newcastle disease virus (NDV) have shown oncolytic therapeutic efficacy in preclinical study and are currently approved for clinical trials. NDV Anhinga strain which is a mesogenic strain should be classified as lytic strain and has a therapeutic efficacy in hepatocellular cancer. In this study, we...