Alleviation of Autophagic Deficits and Neuroinflammation by Histamine H3 Receptor Antagonist E159 Ameliorates Autism-Related Behaviors in <i>BTBR</i> Mice

• Main Authors: Shilu Deepa Thomas (Author), Petrilla Jayaprakash (Author), Nurfirzana Z. H. J. Marwan (Author), Ezzatul A. B. A. Aziz (Author), Kamil Kuder (Author), Dorota Łażewska (Author), Katarzyna Kieć-Kononowicz (Author), Bassem Sadek (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by social interaction difficulties, repetitive behaviors, and immune dysregulation with elevated pro-inflammatory markers. Autophagic deficiency also contributes to social behavior deficits in ASD. Histami...