A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy

• Main Authors: Margo Steuperaert (Author), Charlotte Debbaut (Author), Charlotte Carlier (Author), Olivier De Wever (Author), Benedicte Descamps (Author), Christian Vanhove (Author), Wim Ceelen (Author), Patrick Segers (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although intraperitoneal chemotherapy (IPC) has evolved into an established treatment modality for patients with peritoneal metastasis (PM), drug penetration into tumor nodules remains limited. Drug transport during IPC is a complex process that depends on a large number of different parameters (e.g...