CYP2D6 copy number determination using digital PCR

• Main Authors: Wendy Y. Wang (Author), Lancy Lin (Author), Erin C. Boone (Author), Junko Stevens (Author), Andrea Gaedigk (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundCYP2D6 testing is increasingly used to guide drug therapy and thus, reliable methods are needed to test this complex and polymorphic gene locus. A particular challenge arises from the detection and interpretation of structural variants (SVs) including gene deletions, duplications, and hybr...