Combination of a Chaperone Synthesis Inducer and an Inhibitor of GAPDH Aggregation for Rehabilitation after Traumatic Brain Injury: A Pilot Study

• Main Authors: Elizaveta A. Dutysheva (Author), Elena R. Mikhaylova (Author), Maria A. Trestsova (Author), Alexander I. Andreev (Author), Danila Yu. Apushkin (Author), Irina A. Utepova (Author), Polina O. Serebrennikova (Author), Eugenia A. Akhremenko (Author), Nikolay D. Aksenov (Author), Elizaveta I. Bon' (Author), Sergey M. Zimatkin (Author), Oleg N. Chupakhin (Author), Boris A. Margulis (Author), Irina V. Guzhova (Author), Vladimir F. Lazarev (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The recovery period after traumatic brain injury (TBI) is often complicated by secondary damage that may last for days or even months after trauma. Two proteins, Hsp70 and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), were recently described as modulating post-traumatic processes, and in this st...