Unique pharmacological property of ISRIB in inhibition of Aβ-induced neuronal cell death

• Egile Nagusiak: Toru Hosoi (Egilea), Mai Kakimoto (Egilea), Keigo Tanaka (Egilea), Jun Nomura (Egilea), Koichiro Ozawa (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2016-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A pharmacological approach to ameliorate Alzheimer's disease (AD) has not yet been established. In the present study, we investigated the pharmacological characteristics of the recently identified memory-enhancing compound, ISRIB for the amelioration of AD. ISRIB potently attenuated amyloid β-i...