Development and Evaluation of a Self-Nanoemulsifying Drug Delivery System for Sinapic Acid with Improved Antiviral Efficacy against SARS-CoV-2

• Main Authors: Hani A. Alhadrami (Author), Ahmed S.G. Srag El-Din (Author), Hossam M. Hassan (Author), Ahmed M. Sayed (Author), Albaraa H. Alhadrami (Author), Mostafa E. Rateb (Author), Demiana M. Naguib (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to develop a self-nanoemulsifying drug delivery system (SNE) for sinapic acid (SA) to improve its solubility and antiviral activity. Optimal components for the SA-SNE formulation were selected, including Labrafil as the oil, Cremophor EL as the surfactant, and Transcutol as the co-s...