Acantholysis may precede elevation of circulating anti‐desmoglein 3 antibody levels in pemphigus vulgaris presenting with desquamative gingivitis

• Main Authors: Hiroyasu Endo (Author), Terry D. Rees (Author), Hideo Niwa (Author), Kayo Kuyama (Author), Maya Oshima (Author), Tae Serizawa (Author), Shigeo Tanaka (Author), Masamichi Komiya (Author), Takanori Ito (Author)
• Format: Book
• Published: Wiley, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pemphigus vulgaris (PV) is an autoimmune, blistering disease that affects the mucosa and skin. The current theory favors the concept that anti‐desmoglein (Dsg) 3 autoimmunity is the only pathogenic event needed to induce acantholysis. However, a few cases of active PV in the oral cavity had...