Plasma Extracellular Vesicles-Derived miR-99a-5p: A Potential Biomarker to Predict Early Head and Neck Squamous Cell Carcinoma

• Main Authors: Qiang Huang (Author), Yu-Jie Shen (Author), Chi-Yao Hsueh (Author), Yi-Fan Zhang (Author), Xiao-Hui Yuan (Author), Yu-Juan Zhou (Author), Jiao-Yu Li (Author), Lan Lin (Author), Chun-Ping Wu (Author), Chun-Yan Hu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: This study aimed to investigate the applicability of plasma extracellular vesicles (EVs) miR-99a-5p as a potential head and neck squamous cell carcinoma (HNSCC) diagnostic biomarker.Methods: The miRNA expression of HNSCC tissue and plasma EVs were profiled by small RNA sequencing. qRT-PCR w...