Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders

• Asıl Yazarlar: Androulla N. Miliotou (Yazar), Ioannis S. Pappas (Yazar), George Spyroulias (Yazar), Efthimia Vlachaki (Yazar), Asterios S. Tsiftsoglou (Yazar), Ioannis S. Vizirianakis (Yazar), Lefkothea C. Papadopoulou (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The potential clinical applications of the powerful in vitro-transcribed (IVT)-mRNAs, to restore defective protein functions, strongly depend on their successful intracellular delivery and transient translation through the development of safe and efficient delivery platforms. In this study, an innov...