Investigation of the mechanism of baicalein in the treatment of periodontitis based on network pharmacology, molecular docking and experimental validation

• Main Authors: Yue Liu (Author), Fengdi Cao (Author), Mingyue Shi (Author), Zhuohang Deng (Author), Kaili Guo (Author), Tiantian Fan (Author), Yuhan Meng (Author), Mingyang Bu (Author), Zhe Ma (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose To verify the effect and mechanism of baicalein in the treatment of periodontitis through network pharmacology, molecular docking and in vitro experiments. Methods Firstly, multiple databases were used to predict targets of baicalein and periodontitis. And the screened key target ge...