Genetically modified T cells in cancer therapy: opportunities and challenges

• मुख्य लेखकों: Michaela Sharpe (लेखक), Natalie Mount (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2015-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tumours use many strategies to evade the host immune response, including downregulation or weak immunogenicity of target antigens and creation of an immune-suppressive tumour environment. T cells play a key role in cell-mediated immunity and, recently, strategies to genetically modify T cells either...