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Safety and immunogenicity of a reduced dose of the BNT162b2 mRNA COVID-19 vaccine (REDU-VAC): A single blind, randomized, non-inferiority trial

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Fractional dosing of COVID-19 vaccines could accelerate vaccination rates in low-income countries. Dose-finding studies of the mRNA vaccine BNT162b2 (Pfizer-BioNTech) suggest that a fractional dose induces comparable antibody responses to the full dose in people <55 years. Here, we report the saf...

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Principais autores: Pieter Pannus (Autor), Stéphanie Depickère (Autor), Delphine Kemlin (Autor), Sarah Houben (Autor), Kristof Y. Neven (Autor), Leo Heyndrickx (Autor), Johan Michiels (Autor), Elisabeth Willems (Autor), Stéphane De Craeye (Autor), Antoine Francotte (Autor), Félicie Chaumont (Autor), Véronique Olislagers (Autor), Alexandra Waegemans (Autor), Mathieu Verbrugghe (Autor), Marie-Noëlle Schmickler (Autor), Steven Van Gucht (Autor), Katelijne Dierick (Autor), Arnaud Marchant (Autor), Isabelle Desombere (Autor), Kevin K. Ariën (Autor), Maria E. Goossens (Autor)
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Publicado em: Public Library of Science (PLoS), 2022-01-01T00:00:00Z.
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