Persistent Pulmonary Hypertension of the Newborn: Pathophysiological Mechanisms and Novel Therapeutic Approaches

• Prif Awduron: Sofia Martinho (Awdur), Rui Adão (Awdur), Adelino F. Leite-Moreira (Awdur), Carmen Brás-Silva (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Persistent pulmonary hypertension of the newborn (PPHN) is one of the main causes of neonatal morbidity and mortality. It is characterized by sustained elevation of pulmonary vascular resistance (PVR), preventing an increase in pulmonary blood flow after birth. The affected neonates fail to establis...