Effects of Vitamin B₁₂ Deficiency on Amyloid-β Toxicity in <i>Caenorhabditis elegans</i>

• Main Authors: Arif Andra (Author), Shoko Tanigawa (Author), Tomohiro Bito (Author), Atsushi Ishihara (Author), Fumio Watanabe (Author), Yukinori Yabuta (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High homocysteine (Hcy) levels, mainly caused by vitamin B₁₂ deficiency, have been reported to induce amyloid-β (Aβ) formation and tau hyperphosphorylation in mouse models of Alzheimer's disease. However, the relationship between B₁₂ deficiency and...