Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Ameliorate Aging-Induced BTB Impairment in Porcine Testes by Activating Autophagy and Inhibiting ROS/NLRP3 Inflammasomes via the AMPK/mTOR Signaling Pathway

• Main Authors: Yi Zhou (Author), Jiale Yan (Author), Limin Qiao (Author), Jiaqin Zeng (Author), Fuyu Cao (Author), Xihui Sheng (Author), Xiaolong Qi (Author), Cheng Long (Author), Bingying Liu (Author), Xiangguo Wang (Author), Hua Yao (Author), Longfei Xiao (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As a pivotal player in spermatogenesis, the blood-testis barrier (BTB) made from junction apparatus coexisting in Sertoli cells (SCs) is impaired with an increase in age and ultimately induces spermatogenic dysfunction or even infertility. It has been corroborated that bone marrow mesenchymal stem c...