Experimental colonization with H. hepaticus, S. aureus and R. pneumotropicus does not influence the metabolic response to high-fat diet or incretin-analogues in wildtype SOPF mice

• Main Authors: Margit Wunderlich (Author), Manuel Miller (Author), Bärbel Ritter (Author), Ronan Le Gleut (Author), Hannah Marchi (Author), Monir Majzoub-Altweck (Author), Patrick J. Knerr (Author), Jonathan D. Douros (Author), Timo D. Müller (Author), Markus Brielmeier (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: We here assessed whether typical pathogens of laboratory mice affect the development of diet-induced obesity and glucose intolerance, and whether colonization affects the efficacy of the GLP-1R agonist liraglutide and of the GLP-1/GIP co-agonist MAR709 to treat obesity and diabetes. Meth...