Dried Blood Spots in Neonatal Studies: A Computational Analysis for the Role of the Hematocrit Effect

• Main Authors: Chrysa Daousani (Author), Vangelis Karalis (Author), Yannis L. Loukas (Author), Kleopatra H. Schulpis (Author), Konstantinos Alexiou (Author), Yannis Dotsikas (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dried blood spot (DBS) microsampling is extensively employed in newborn screening (NBS) and neonatal studies. However, the impact of variable neonatal hematocrit (Ht) values on the results can be a source of analytical error, and the use of fixed Ht for calibration (Ht_cal) is...